This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Pneumococcal bacteria (Streptococcus pneumoniae) can cause several different serious infections including pneumonia, sinusitis, and meningitis. Studies to monitor the levels of pneumococcal bacteria ‘carried’ by individuals are called carriage studies and are used to inform vaccination programs. But most carriage study techniques distinguish between pneumococcal subtypes based on their outside structure, or serotype, rather than by genetic strain. Consequently, little is known about strain-specific carriage and interactions between strains. To close this gap, researchers trialed a new workflow using single-molecule real-time (SMRT) sequencing of the genetic marker plyNCR. Tests using mock bacterial communities found that this workflow was sensitive and highly specific to S. pneumoniae. Banked nasal swabs collected from infants during their first year of life were used for a real-world test..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
- Subject:
- Biology
- Life Science
- Material Type:
- Diagram/Illustration
- Reading
- Provider:
- Research Square
- Provider Set:
- Video Bytes
- Date Added:
- 04/14/2023